United States Department of Veterans Affairs
Research Advisory Committee on Gulf War Veterans' Illnesses

Research Update - February 2007

The following journal articles were distributed for review in February 2007.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here.

Research Relevant to Gulf War Service and Exposures
 
1. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms.  (Block ML, et al.  Nat Rev Neurosci. Jan 2007; 8(1):57-69)
 
2. Impact of phlebotomine sand flies on US military operations at Tallil Air Base, Iraq: 2. Temporal and geographic distribution of sand flies.  (Coleman RE, et al.  J Med Entomol.  Jan 2007; 44(1): 29-41)
 
3. Effects of combined exposure to pyridostigmine bromide and shaker stress on acoustic startle response, pre-pulse inhibition and open field behavior in mice.  (Dubovicky M, et al.  J Appl Toxicol.  Jan 30, 2007; [Epub ahead of print])
 
4. Screening for peripheral neuropathy in chemical warfare victims.  (Holisaz MT , et al.  Int J Rehabil Res.  Mar 2007; 30(1): 71-74)
 
5. Iraqi Gulf War veteran refugees in the US: PTSD and physical symptoms.  (Jamil H, et al.  Soc Work Health Care.  2006; 43(4): 85-98)
 
6. Gulf War depleted uranium risks.  (Marshall AC.  J Expo Sci Environ Epidemiol.  Feb 14, 2007 ; [Epub ahead of print])
 
7. Toxicodynamic modeling of highly toxic organophosphorous compounds.  (Maxwell DM, et al.  J Mol Neurosci .  2006; 30(1-2): 129-131)
 
8. Controlling inflammation: the cholinergic anti-inflammatory pathway.  (Pavlov VA , Tracey KJ.  Biochem Soc Trans.  Dec 2006; 34(Pt 6): 1037-1040)
 
9. Long- and short-term changes in the neuroimmune-endocrine parameters following inhalation exposures of F344 rats to low-dose sarin.  (Pena-Philippides JC, et al.  Toxicol Sci.  Feb 14, 2007; [Epub ahead of print])

Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
 
1. Decreased pain and improved quality of life in fibromyalgia patients treated with olanzapine, an atypical neuroleptic.  (Freedenfeld RN, et al.  Pain Pract.  Jun 2006; 6(2): 112-118)
 
2. Is human herpesvirus-6 a trigger for chronic fatigue syndrome?  (Komaroff AL.  J Clin Virol.   Dec 2006; 37 Suppl 1: S39-S46)
 
3. A cross-sectional study of self-reported chemical-related sensitivity is associated with gene variants of drug metabolizing enzymes.  (Schnakenberg E, et al.  Environ Health.  Feb 10, 2007; 6(1): 6 [Epub ahead of print])