United States Department of Veterans Affairs
Research Advisory Committee on Gulf War Veterans' Illnesses

Research Update - May 2006

The following journal articles were distributed for review in May 2006.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here. 

Research Relevant to Gulf War Service and Exposures
 
1. Interpreting symptoms in military personnel after combat.   (Axelrod BN.  Lancet.  May 16, 2006; [Epub ahead of print])
 
2. Veterans Administration. Texas earmark allots millions to disputed theory of Gulf War illness.   (Couzin J.  Science.  May 5, 2006; 312(5774): 668)
 
3. Psychiatric disorder and separation from military service: a 10-year retrospective study.   (Creamer M, et al.  Am J Psychiatry.  Apr 2006; 163(4): 733-734)
 
4. Toxicogenomic studies of rat brain at an early time point following acute sarin exposure.   (Damodaran TV, et al.  Neurochem Res.  May 13, 2006; [Epub ahead of print])
 
5. Depleted uranium is not toxic to rat brain endothelial (RBE4) cells.   (Dobson AW, et al.  Biol Trace Elem Res.  Apr 2006; 110(1): 61-72)
 
6. Military deployment to the Gulf War as a risk factor for psychiatric illness among US troops.   (Fiedler N, et al.  Br J Psychiatry.  May 2006; 188: 453-459)
 
7. Posttraumatic stress disorder among military returnees from Afghanistan and Iraq.   (Friedman MJ.  Am J Psychiatry.  Apr 2006; 163(4): 586-593)
 
8. Neurology in Operation Iraqi Freedom: risk factors for referral, clinical presentations and incidence of disease.   (Hartmann JE.  J Neurol Sci.  Feb 2006; 241(1-2): 83-90)
 
9. Is there an Iraq war syndrome? Comparison of the health of UK service personnel after the Gulf and Iraq wars.   (Horn O, et al.  Lancet.  May 16, 2006; [Epub ahead of print])
 
10. The health of UK military personnel who deployed to the 2003 Iraq war: a cohort study.   (Hotopf M, et al.  Lancet.  May 16, 2006; [Epub ahead of print])
 
11. Consent, confidentiality, and the Data Protection Act.   (Iversen A, et al.  BMJ.  Jan 21, 2006; 332(7534): 165-169)
 
12. Neurotoxicity of depleted uranium: reasons for increase concern.   (Jiang GC, Aschner M.  Biol Trace Elem Res.  Apr 2006; 110(1): 1-18)
 
13. Multiplex analysis of circulating cytokines in the sera of patients with different clinical forms of visceral leishmaniasis.   (Kurkjian KM, et al.  Cytometry A.  Apr 7, 2006; [Epub ahead of print])
 
14. GSTP1 genetic polymorphism is associated with a higher risk of DNA damage in pesticide-exposed fruit growers.   (Liu YJ, et al.  Cancer Epidemiol Biomarkers Prev.  Apr 2006; 15(4): 659-666)
 
15. Effect of pyridostigmine, pralidoxime and their combination on survival and cholinesterase activity in rats exposed to the organophosphate paraoxon.   (Petroianu GA , et al.  Arch Toxicol.  Apr 6, 2006; [Epub ahead of print])
 
16. Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.   (Rothlein J, et al.  Environ Health Perspect.  May 2006; 114(5): 691-696)
 
17. Initial evaluation of N, N-diethyl-m-toluamide and permethrin absorption in human volunteers under stress conditions.   (Roy MJ, et al.  Mil Med  Feb 2006; 171(2): 122-127)
 
18. Cerebral acetylcholine and choline contents and turnover following low-dose acetylcholinesterase inhibitors treatment in rats.   (Shih TM, et al.  Arch Toxicol.  Apr 21, 2006; [Epub ahead of print])
 
19. Neuropsychological effects of long-term low-level organophosphate exposure in orchard sprayers in England.  (Stephens R, Sreenivasan B.  Arch Environ Health.  Nov 2004; 59(11): 566-574)
 
20. The Neurocognition Deployment Health Study: a prospective cohort study of Army soldiers.   (Vasterling JJ, et al.  Mil Med.  Mar 2006; 171(3): 253-260)
 
21. Hippocampal volume, PTSD, and alcoholism in combat veterans.   (Woodward SH, et al.  Am J Psychiatry.  Apr 2006; 163(4): 674-681)
 
22. Plasma neuropeptide Y concentrations in combat exposed veterans: relationship to trauma exposure, recovery from PTSD, and coping.   (Yehuda R, et al.  Biol Psychiatry.  Apr 1, 2006; 59(7): 660-663)

Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
 
1. Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology.   (Cho HJ, et al.  Curr Opin Psychiatry.  Jan 2006; 19(1): 67-73)
 
2. Explanatory and pragmatic perspectives regarding idiopathic physical symptoms and related syndromes.   (Engel CC.  CNS Spectr.  Mar 2006; 11(3): 225-232)
 
3. Antidepressants and cognitive-behavioral therapy for symptom syndromes.   (Jackson JL, et al.  CNS Spectr.  Mar 2006; 11(3): 212-222)
 
4. The challenge of integrating disparate high-content data: epidemiological, clinical and laboratory data collected during an in-hospital study of chronic fatigue syndrome.   (Vernon SD , Reeves WC.  Pharmacogenomics.  Apr 2006; 7(3): 345-354) (NOTE: This issue of Pharmacogenomics contains 18 other articles relating to a program sponsored by CDC to evaluate and integrate a large amount of genomic and clinical information on chronic fatigue syndrome patients from a community-based study.) 
 
5. Slow-frequency rTMS reduces fibromyalgia pain.   (Sampson SM, et al.   Pain Med.  Mar 2006; 7(2): 115-1118)
 

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