United States Department of Veterans Affairs
Research Advisory Committee on Gulf War Veterans' Illnesses

Research Update - October 2006

The following journal articles were distributed for review in October 2006.  You can access the article's abstract by copying the paper title and pasting it into the search bar of the PubMed website, linked here. 

Research Relevant to Gulf War Service and Exposures
 
1. Effects of combined, multiple stressors on pyridostigmine-induced acute toxicity in rats.  (Baireddy P, et al.  Arch Toxicol.  Aug 30, 2006; [Epub ahead of print])
 
2. Depleted uranium: all the questions about DU and Gulf War syndrome are not yet answered.  (Bertell R.  Int J Health Serv.  2006; 36(3): 503-520)
 
3. Borderline personality disorder and traits in veterans – psychiatric comorbidity, healthcare utilization, and quality of life along a continuum of severity.  (Black DW, et al.  CNS Spectr.  Sep 2006; 11(9): 680-689)
 
4. Long-term changes of serum chemokine levels in vaccinated military personnel.  (Brichacek B, et al.  BMC Immunol.  Sep 11, 2006; 7(1): 21 [Epub ahead of print])
 
5. Gulf war symptoms do not constitute a syndrome.  (Charatan F.  BMJ.  Sep 23, 2006; 333(7569): 618)
 
6. Vaccines with the MF59 adjuvant do not stimulate antibody responses against squalene.  (Del Giudice G, et al.  Clin Vaccine Immunol.  Sep 2006; 13(9): 1010-1013)
 
7. Absorption, accumulation and biological effects of depleted uranium in Peyer’s patches of rats.  (Dublineau I, et al.  Toxicology.  Aug 17, 2006; [Epub ahead of print])
 
8. Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults.  (Evron T, et al.  Toxicology.  Aug 22, 2006; [Epub ahead of print])
 
9. Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets.  (Fitsanakis VA , et al.  Biol Trace Elem Res.  Summer 2006; 111(1-3): 185-197)
 
10. Fatal motor vehicle crashes among veterans of the 1991 Gulf War and exposure to munitions demolitions at Khamisiyah: a nested case-control study.  (Gackstetter GD, et al.  Am J Ind Med.  Apr 2006; 49(4): 261-270)
 
11. The ACTH response to dexamethasone in Persian Gulf War veterans.   (Golier JA, et al.  Ann N Y Acad Sci.  Jul 2006; 1071: 448-453)
 
12. A reevaluation of the threshold exposure level of inhaled JP-8 in mice.  (Herrin BR, et al.  J Toxicol Sci.  Aug 2006; 31(3): 219-228)
 
13. Post-traumatic stress disorder in UK and US forces deployed to Iraq.  (Hoge CW, Castro CA.  Lancet.  Sep 2, 2006; 368(9538): 837)
 
14. Is there an Iraq war syndrome?  (Holdstock D.  Lancet.  Sep 2, 2006; 368(9538): 837-838)
 
15. Is there an Iraq war syndrome?  (Horn O, Wessely S.  Lancet.  Sep 2, 2006; 368(9638): 838)
 
16. Post-traumatic stress disorder in UK and US forces deployed to Iraq – Author’s reply.  (Hotopf M, et al.  Lancet.  Sep 2, 2006; 368(9638): 837)
 
17. Multi-drug resistant Acinetobacter spp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center: analysis of antibiotic resistance genes.  (Hujer KM, et al.  Antimicrob Agents Chemoter.  Sep 25, 2006; [Epub ahead of print])
 
18. Re: “Chronic multisymptom illness complex in Gulf War I veterans 10 years later.”  (Hunt SC , et al.  Am J Epidemiol.  Aug 30, 2006; [Epub ahead of print])
 
19. Interpreting symptoms in military personnel after combat.  (Jones R.  Lancet.  Sep 2, 2006; 368(9538): 838)
 
20. Sarin produces delayed cardiac and central autonomic changes.  (Morris M, et al.  Exp Neurol.  Sep 21, 2006; [Epub ahead of print])
 
21. Effects of sarin and cyclosarin exposure during the 1991 Gulf War on neurobehavioral functioning in US army veterans.  (Proctor SP, et al.  Neurotoxicology.  Aug 7, 2006; [Epub ahead of print])
 
22. Mental health screening in armed forces before the Iraq war and prevention of subsequent psychological morbidity: follow-up study.  (Rona RJ, et al.  BMJ.  Oct 5, 2006; [Epub ahead of print[)
 
23. Using a white matter reference to remove the dependency of global signal on experimental conditions in SPECT analyses.  (Spence JS, et al.  Neuroimage.  Aug 1, 2006; 32(1): 49-53.  [Epub May 2, 2006])
 
24. Pain in veterans of the Gulf War of 1991: a systematic review.  (Thomas HV, et al.  BMC Musculoskelet Disord.  Sep 20, 2006; 7(1): 74 [Epub ahead of print])
 
25. Military hospitalizations among deployed US service members following anthrax vaccinations, 1998-2001.  (Wells TS, et al.  Hum Vaccin.  Mar 13, 2006; [Epub ahead of print])
 
26. Sarin experiences in Japan:  Acute toxicity and long-term effects.  (Yanagisawa N, et al.  J Neurol Sci.  Sep 5, 2006; [Epub ahead of print])
 

Research on Evaluation/Treatment of Chronic Multisymptom Illnesses
 
1. Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens:  prospective cohort study.  (Hickie I, et al.  BMJ.  Sep 1, 2006; [Epub ahead of print])
 
2. Cognitive behavioural therapy in chronic fatigue syndrome: a randomized controlled trial of an outpatient group programme.  (O’Dowd H, et al.  Health Technol Assess.  Oct 2006; 10(37): 1-140)
 
3. Pharmacologic management of complex regional pain syndrome.  (Rowbotham MC.  Clin J Pain.  Jun 2006; 22(5): 425-429)
 
4. A reconsideration of the relevance of systemic low-dose ketamine to the pathophysiology of fibromyalgia.  (Wood PB.  J Pain.  Sep 2006; 7(9): 611-614)
 
5. Reduced presynaptic dopamine activity in fibromyalgia syndrome demonstrated with positron emission tomography: a pilot study.  (Wood PB, et al.  J Pain.  Oct 3, 2006; [Epub ahead of print])

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