THE EFFECTS OF EXERCISE ON INSULIN SENSITIVITY IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Project Background

PCOS is a common disorder affecting up to 10% of young women and recent studies have documented a significant insulin resistance in this population.

Project Objectives

This career development proposal details a plan for Dr. Brown to obtain didactic training and research experience with Polycystic ovary syndrome (PCOS)

Project Methods

In a randomized controlled clinical trial, this study will seek to examine does a 12 week program of monitored exercise of moderate intensity, without weight loss, significantly improve insulin sensitivity as measured by an intravenous glucose tolerance test? What is the relative magnitude of the acute effect compared to the chronic effect of exercise on insulin sensitivity? Does exercise that reduces insulin resistance also decrease androgen levels? Does exercise improve indicators of perceived body image, quality of life, stress and depression?

Project Findings

On-going enrollment.

Project Status

Project work is ongoing.

Project Impact

PCOS is a common disorder affecting up to 10% of young women. This study will provide Dr. Brown with experience necessary to develop an independent career as a clinical investigator as well as develop a randomized controlled clinical trial that will help reduce insulin resistance among women with PCOS.

Stroke QUERI Executive Committee | Stroke QUERI Strategic Plan FY2007 | Stroke QUERI Organizational Chart | Contact the Stroke QUERI Center | Contact the Stroke QUERI Webmaster