THE HOME INTERNATIONAL NORMALIZED RATIO (INR) MONITOR STUDY (THINRS)

Project Background

This study is to evaluate patient self-testing of prothrombin time using a home monitoring device and conventional PT monitoring.

Project Objectives

To compare anticoagulation management with frequent patient self-testing of prothrombin time using a home monitoring device with conventional Pt monitoring on major health outcomes: stroke, major bleed, and mortality.

Project Methods

Thirty two VA Medical Centers will participate in the study and it will be conducted in two parts. Part 1: Candidates for PST will be evaluated over a 2-week period for their ability to use the home-monitoring devices. Part 2: The duration of this part of the study will be for two years, 3200 consenting and eligible subjects from Part 1 will be randomized to one of two arms.

Project Findings

none at this time.

Project Status

Ongoing.

Project Impact

This study will help determine is home monitoring of PT improves patient's health and be more cost-effective.

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