Hung-Yun Lin, Ph.D.
- Research Scientist, Stratton VA Medical Center
Education
- Ph.D., Microbiology, State University of New York at Buffalo
Research Focus
Research focuses on p53-dependent apoptosis in human cancers, especially interested in manipulating mutant p53 to restore its cancer suppressor activity.
Selected Recent Publications
Lin, H. Y., Shih, A., Davis, F.B., Tang, H.-Y., Bennett, J., and Davis, P.J. (2002). Resveratrol-induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line. J Urol. 168:748-755.
Lin, H.Y., Zhang, S.L., West, B.L., Tang, H.-Y., Passaretti, T., Davis, F.B., and Davis, P. (2003). Identification of the putative MAP kinase docking site in the thyroid hormone receptor-ß1 DNA binding domain: Functional consequences of mutations at the docking site. Biochemistry 42:7571-7579.
Lin, H.Y., Michtalik, H.J., Zhang, S, Andersen, T.T., Van Riper, D.A., Davies, K.K., Ermak, G., Petti, L.M., Nachod, S., Narayan, A.V., Bhatt, N., and Crawford, D.R. (2003). Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein. Free Radic Biol Med. 35:528-539.
Shih, A., Zhang, S.L., Cao, H. J., Tang, H.-Y., Davis, F.B., Davis, P.J., and Lin, H.Y. (2004). Disparate effects of thyroid hormone on actions of epidermal growth factor and transforming growth factor-alpha are mediated by 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase II. Endocrinology145:1708-1717.
Zhang, S. L., Cao, J. H., Davis, F. B., Tang, H. Y., Davis, P. J., and Lin, H. Y. (2004). Estrogen inhibits resveratrol-induced posttranslational modification of p53 and apoptosis in breast cancer cells. Brit. J. Cancer, In press.
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Address
608 Core Research Service
Stratton VA Medical Center
113 Holland Avenue
Albany, NY 12208
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Phone
(518) 626-5669
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