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VA Healthcare Network Upstate New York - VISN 2
Diuretics for High Blood Pressure
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What is High Blood Pressure?
A blood pressure of 140/90 mmHg or higher is considered
high blood pressure. [A blood pressure of 130/80
mmHg or higher is considered high blood pressure in
people with diabetes and chronic kidney disease.] Both
numbers are important. If one or both numbers are
usually high, you have high blood pressure.
Nearly 1 in 3 American adults has high blood pressure.
Once high blood pressure develops, it usually lasts a
lifetime. The good news is that it can be treated and
controlled.
High blood pressure is called the silent killer because
it usually has no symptoms. Some people may not find
out they have it until they have trouble with their heart,
brain, or kidneys. When high blood pressure is not
found and treated, it can cause:
- The heart to get larger, which may lead to heart
failure.
- Small bulges (aneurysms) to form in blood vessels.
Common locations are the main artery from the
heart (aorta); arteries in the brain, legs, and intestines;
and the artery leading to the spleen.
- Blood vessels in the kidney to narrow, which may
cause kidney failure.
- Arteries throughout the body to “harden” faster, especially
those in the heart, brain, kidneys, and legs.
This can cause a heart attack, stroke, kidney failure,
or amputation of part of the leg.
- Blood vessels in the eyes to burst or bleed, which
may cause vision changes and can result in blindness.
Blood pressure changes during the day. It is lowest as
you sleep and rises when you get up. It also can rise
when you are excited, nervous, or active. Still, for
most of your waking hours, your blood pressure stays
pretty much the same when
you are sitting or standing still.
That level should be lower than
120/80 mmHg. When the level
stays high, 140/90 mmHg or
higher, you have high blood
pressure. With high blood pressure,
the heart works harder,
your arteries take a beating, and
your chances of a stroke, heart attack, and kidney
problems are greater.
Blood pressure should be controlled to less than
140/90 mm Hg--even lower if you have certain conditions,
such as diabetes or heart failure.
If you are being treated for high blood pressure and
have repeated readings in the normal range, you still
have high blood pressure.
Every drug has multiple effects, and the benefits of its
use must be weighed against the risks to find the best
treatment for each person. Treatment includes lifestyle
measures, such as becoming physically active, losing
weight, if overweight, following a low-saturated fat,
low-cholesterol eating plan, limiting dietary salt, and
not smoking. Drug therapy may not be needed.
New Findings about Drugs to Lower
High Blood Pressure
Many drugs have been developed in recent years to
treat high blood pressure, a major risk factor for heart
disease. Recent findings from a major clinical study
supported by the National Heart, Lung, and Blood Institute
(NHLBI) offer new information about treatment.
The “Antihypertensive and Lipid-Lowering Treatment
to Prevent Heart Attack Trial” (ALLHAT) was a large
study that began in 1994 and lasted 8 years. It had two
parts: one compared effects of a diuretic (sometimes
referred to as a “water pill”) with three newer, more
costly blood pressure-lowering drugs; the other compared
the effects of a cholesterol-lowering statin drug
and diet with those of “usual care.” The blood pressure
trial involved more than 40,000 persons, aged 55 and
older, who had high blood pressure.
If you are being treated for high blood pressure and/or
high cholesterol, do not make any changes without
first talking with your doctor.
All four of the drugs studied in ALLHAT are effective in
lowering blood pressure. The study tried to find which
was the best choice for starting treatment. Results show
that diuretics work best to both lower blood pressure
and prevent stroke and some forms of heart disease,
including heart attack and heart failure. The advice
given here also includes another type of blood pressure
drug called beta blockers. This drug was not studied in
ALLHAT but prior trials found it effectively lowers blood
pressure, and prevents heart problems and strokes.
Results to Guide You:
- If you need to begin drug treatment, you should
definitely try a diuretic first. [The most commonly
prescribed diuretic used for hypertension in the VA
system is hydrochlorothiazide (HCTZ)]
- Beta blockers are another option to begin treatment,
especially if you’re younger than age 60 and do not
have diabetes or peripheral artery disease (in which
blood flow becomes reduced, especially to the hands
and feet). Beta blockers also may be needed if you’re
taking the drug for another condition, such as heart
attack or heart failure. If you’re now taking a beta
blocker, talk with your doctor about your total health
needs.
- If you need multiple drugs to control your blood pressure-
which is common-make sure one is a diuretic. If
you already take more than one drug but your blood
pressure is not yet under control, talk with your doctor
about adding a diuretic to your treatment. If you
take more than one drug and your blood pressure is
controlled, ask about switching one to a diuretic.
- Your doctor may consider giving you a calcium
channel blocker or ACE inhibitor if you cannot take
a diuretic.
If you have angina (chest pain from heart disease), you
may need to take a beta-blocker, a calcium channel
blocker, or both. These medications are often used in
combination with a diuretic for associated heart conditions.
Check with your doctor.
Your doctor may consider prescribing an alpha-blocker
if you take more than one drug to control blood pressure
and you also have Benign Prostatic Hyperplasia.
Talk with your doctor about your total health needs.
To Learn More
Ask your primary care provider
if you have questions about your
blood pressure or the drugs
that you are taking to treat
high blood pressure. If you have
questions, an appointment can
be made for you.
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| Reviewed/Updated Date: December 13, 2007 |
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